Saudi Arabia has another case of new coronavirus: WHO

LONDON | Sat May 18, 2013 5:43pm EDT

LONDON (Reuters) – Saudi Arabia has reported another case of infection in a concentrated outbreak of a new strain of a virus that emerged in the Middle East last year and spread into Europe, the World Health Organization (WHO) said on Saturday.

In a disease outbreak update issued from its Geneva headquarters, the WHO said the latest patient is an 81-year-old woman with multiple medical conditions. She became ill on April 28 and is in a critical but stable condition.

Worldwide, there have now been 41 laboratory-confirmed infections, including 20 deaths, since the new coronavirus was identified by scientists in September 2012.

The novel coronavirus, which had been known as by the acronym nCoV but which some scientific journals now refer to as Middle East Respiratory Syndrome coronavirus, or MERS, belongs to the same family as viruses that cause common colds and the one that caused a deadly outbreak of Severe Acute Respiratory Syndrome (SARS) in 2003.

MERS cases have so far been reported in Saudi Arabia, Jordan, Qatar, Britain, Germany and France, but Saudi Arabia has had the vast majority of cases.

The WHO said that latest patient was in the same clinic in eastern Saudi Arabia that has seen 22 cases, nine of them fatal, since April 8.

Rubella fears after measles epidemic

17 May 2013 Last updated at 07:39 ET

Pregnant womanPregnant women could suffer complications with their unborn children if they catch rubella

Health officials have warned that action is needed to prevent a rubella outbreak, which can be particularly dangerous to pregnant women.

Public Health Wales and national deaf-blind charity Sense say about 38,000 young people in Wales have not had the measles mumps and rubella (MMR) jab.

They welcomed the efforts to increase vaccinations in light of the measles epidemic centred on Swansea.

But they said more people need to have the recommended two doses.

The measles epidemic has seen 1,094 cases reported in the Swansea area, with 1,257 across Wales.

If rubella is contracted by a pregnant woman, it can cause babies to be born with combined sight and hearing loss along with life-threatening heart conditions and a long list of other health issues.

Joff McGill, of Sense, said: “We can’t sit around and wait for rubella outbreaks to follow measles – now is the time to catch up and stay ahead of rubella.

“We must act now to protect pregnant women and their unborn babies. Women who are unsure of their vaccination history and are thinking about becoming pregnant should contact their GP for advice.”

Mr McGill added: “The large group of 38,000 unvaccinated young people in Wales, along with evidence of increasing susceptibility to rubella in younger woman and in women from ethnic minorities, means immunisation can no longer be a childhood issue.

Lundbeck says drug shows improvement in depression symptoms

COPENHAGEN | Sat May 18, 2013 2:05pm EDT

COPENHAGEN (Reuters) – Danish pharmaceutical group Lundbeck and Japanese partner Takeda said on Saturday that data from clinical phase III studies with the antidepressant vortioxetine had shown significant improvement in patients’ symptoms.

Lundbeck said in a statement that the trial showed safety levels consistent with previously completed studies at lower doses.

Lundbeck and Takeda submitted vortioxetine, also known as Brintellix, for regulatory approval in the United States and Europe at the end of last year.

Industry analysts at Deutsche Bank see the new drug having sales potential in excess of $1.5 billion and possibly up to $3 billion a year, although consensus forecasts for 2016 are a more modest $500 million, according to Thomson Reuters Pharma.

Lundbeck hopes the new drug will provide a new source of revenue as its existing antidepressant, Cipralex, sold as Lexapro in the United States and Japan, comes off patent protection.


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Virus found in Iowa hog population, possibly beyond

WASHINGTON | Fri May 17, 2013 5:17pm EDT

WASHINGTON (Reuters) – USDA’s National Veterinary Services Laboratories has detected porcine epidemic diarrhea (PEDV), a virus associated with outbreaks of diarrhea and vomiting, in the Iowa hog population, a USDA spokesman said on Friday.

The virus is not a food safety concern and does not affect humans, the spokesman said.

Officials with USDA’s Animal and Plant Health Inspection Service (APHIS) held a call with livestock industry representatives on Friday to discuss the situation. It was not immediately clear how widespread the incidence of PEDV is at this point.

There are currently no interstate trade restrictions related to PEDV for U.S. hogs and pigs.

Hog futures in Chicago fell sharply on Friday as rumors swirled that the disease had been detected in Iowa and Minnesota. USDA so far has only confirmed detection of PEDV in Iowa.

PEDV exists in many parts of the world, including England, much of Europe, China, Taiwan and South Korea, according to Iowa State University. It closely resembles transmissible gastroenteritis (TGE) in swine.


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Time-lapse imaging 'improves IVF'

16 May 2013 Last updated at 21:49 ET

Fergus Walsh, Medical correspondent Article written by Fergus Walsh Medical correspondent

embryo under microscopeThis technique allows thousands of images of the early embryo to be taken

Time-lapse imaging which takes thousands of pictures of developing embryos can boost the success rate of IVF, according to British research.

The method, reported in Reproductive BioMedicine Online, can be used to select embryos at low risk of defects.

Scientists at the CARE fertility group say such informed selection can improve birth rates by 56%.

Other experts say the result is exciting, but the study of 69 couples is too small to be definitive.

The research followed the couples at the CARE fertility clinic in Manchester last year, when 88 embryos were imaged and implanted.

The embryos were put into an incubator and imaged every 10-20 minutes.

Continual embryo monitoring through time-lapse imaging is aimed at selecting those with the lowest risk of aneuploidy – where the cells have chromosome abnormalities. Aneuploidy is the single biggest cause of IVF failure.

But this form of embryo screening is a predictive rather than diagnostic tool.

Couples at high risk of passing on a chromosomal abnormality may prefer to have Pre-implantation Genetic Screening. This invasive test removes cells from the early embryo for analysis. It costs around £2,500 on top of the £3,000 charged for conventional IVF.

The researchers classified the embryos as low, medium or high risk of chromosome abnormalities based on their development at certain key points.