Men With Erection Problems Are Three Times More Likely To Have Inflamed Gums

Main Category: Erectile Dysfunction / Premature Ejaculation
Also Included In: Dentistry
Article Date: 04 Dec 2012 – 0:00 PST

Men With Erection Problems Are Three Times More Likely To Have Inflamed Gums

Men in their thirties who had inflamed gums caused by severe periodontal disease were three times more likely to suffer from erection problems, according to a study published in the Journal of Sexual Medicine.

Turkish researchers compared 80 men aged 30 to 40 with erectile dysfunction with a control group of 82 men without erection problems.
This showed that 53 per cent of the men with erectile dysfunction had inflamed gums compared with 23 per cent in the control group.
When the results were adjusted for other factors, such as age, body mass index, household income and education level, the men with severe periodontal disease were 3.29 times more likely to suffer from erection problems than men with healthy gums.
“Erectile dysfunction is a major public health problem that affects the quality of life of some 150 million men, and their partners, worldwide,” says lead author Dr. Faith Oguz from Inonu University in Malatya, Turkey.
“Physical factors cause nearly two-thirds of cases, mainly because of problems with the blood vessels, with psychological issues like emotional stress and depression accounting for the remainder.
“Chronic periodontitis (CP) is a group of infectious diseases caused predominantly by bacteria that most commonly occur with inflammation of the gums.
“Many studies have reported that CP may induce systemic vascular diseases, such as coronary heart disease, which have been linked with erection problems.”
The average age of the men in both groups was just under 36 and there were no significant differences when it came to body mass index, household income and education.
Their sexual function was assessed using the International Index of Erectile Function and their gum health using the plaque index, bleeding on probing, probing depth and clinical attachment level.

Following Radiation In Prostate Cancer, Risk Markers Discovered For Erectile Dysfunction

Main Category: Prostate / Prostate Cancer
Also Included In: Erectile Dysfunction / Premature Ejaculation;  Radiology / Nuclear Medicine
Article Date: 29 Sep 2012 – 0:00 PDT

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Following Radiation In Prostate Cancer, Risk Markers Discovered For Erectile Dysfunction

In the first study of its kind, a research team led by Mount Sinai School of Medicine and Albert Einstein College of Medicine of Yeshiva University discovered 12 genetic markers associated with the development of erectile dysfunction (ED) in prostate cancer patients who were treated with radiation. The findings, published online in advance of the October 1, 2012 print issue in the International Journal of Radiation Oncology• Biology• Physics, the official scientific journal of the American Society for Radiation Oncology, are an important step towards helping clinicians determine the best course of treatment for prostate cancer patients and may lead to the development of therapies that alleviate side effects.

Knowledge Of The Biochemical Events Needed To Maintain Erection May Lead To New Therapies For Erectile Dysfunction

Main Category: Erectile Dysfunction / Premature Ejaculation
Article Date: 28 Sep 2012 – 0:00 PDT

Knowledge Of The Biochemical Events Needed To Maintain Erection May Lead To New Therapies For Erectile Dysfunction

For two decades, scientists have known the biochemical factors that trigger penile erection, but not what’s needed to maintain one. Now an article by Johns Hopkins researchers, scheduled to be published this week by the Proceedings of the National Academy of Sciences (PNAS), uncovers the biochemical chain of events involved in that process. The information, they say, may lead to new therapies to help men who have erectile dysfunction.

“We’ve closed a gap in our knowledge,” says Arthur Burnett, M.D., professor of urology at Johns Hopkins Medicine and the senior author of the study article. “We knew that the release of the chemical nitric oxide, a neurotransmitter that is produced in nerve tissue, triggers an erection by relaxing muscles that allow blood to fill the penis. We thought that was just the initial stimulus. In our research, we wanted to understand what happens next to enable that erection to be maintained.”

In a study of mice, Burnett and his colleagues found a complex positive feedback loop in the penile nerves that triggers waves of nitric oxide to keep the penis erect. He says they now understand that the nerve impulses that originate from the brain and from physical stimulation are sustained by a cascade of chemicals that are generated during the erection following the initial release of nitric oxide. “The basic biology of erections at the rodent level is the same as in humans,” he says.

Predicting Erectile Dysfunction From Prostate Cancer Treatment

Cardiometabolic Risks And Sexual Health

Main Category: Cardiovascular / Cardiology
Also Included In: Erectile Dysfunction / Premature Ejaculation;  Heart Disease;  Men’s Health
Article Date: 03 Sep 2012 – 0:00 PDT

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Assessment of sexual function should be incorporated into cardiovascular risk evaluation for all men, regardless of the presence or absence of known cardiovascular disease, according to Dr. Ajay Nehra, lead author of a report by the Princeton Consensus (Expert Panel) Conference, a collaboration of 22 international, multispecialty researchers. Nehra is vice chairperson, professor and director of Men’s Health in the Department of Urology at Rush University Medical Center in Chicago.

Erectile dysfunction (ED) is a red flag in younger men, less than 55 years of age for future cardiac morbidity or mortality – death or disease – for cardiovascular disease (CVD). In some patients, the time window between onset of ED and a cardiovascular event may be two to five years.

“Any man with ED should be considered at a substantially higher increase cardiovascular risk until further testing can be done,” said Nehra. “Erectile dysfunction often occurs in the presence of silent, non-symptomatic cardiovascular disease; and hence this is an opportunity for cardiovascular risk reduction.”

The panel recommends that younger men, more than 30 years old who experience ED receive a thorough, non invasive cardiovascular disease evaluation. As the consensus panel considers all men with ED who are older than 30 to be at increased CVD risk, a thorough noninvasive and, when indicated, invasive evaluation of CVD status is recommended.